The 6 Best Vitamins for Men Over 40


Why should we differentiate between vitamins for men over 40 and those made for younger men? 

For starters, men over 40 become progressively less efficient at producing their own vitamin D, vitamin B12, testosterone, and several other key nutrients/compounds.

Older men are also at a greater risk for prostate cancer, bone health decline, hair loss, vision problems, heart health challenges, and many, many other rites of aging. 

But there’s no reason to weep and wail in self-pity if you’re a man entering the “silver fox” era, because along with a healthy diet and exercise, there are plenty of vitamins for men over 40 that can drastically improve your overall health as you age.

Here’s our list of the 6 best vitamins for men over 40, selected for their nutritional density, formulation quality, value, and more.

TNI Main Logo 700x432 1 Best Overall
Solaray Men’s Golden Multivitamin
Hi-Health Men’s Multi
Best Absorption
New Chapter One Daily Every Man’s Multivitamin
Product Solaray Hi-Health New Chapter
Description 20+ vitamins, trace minerals, and other essential nutrients; men’s herbal support complex with alfalfa herb and saw palmetto; biotin and zinc for hair loss prevention 40+ essential vitamins and minerals including vitamin D, vitamin B12, and more to cover nutrient gaps; plant extracts; energy support complex with green tea, rosemary, rutin, etc.; saw palmetto and nettle leaf extract; trace minerals Non-GMO Project and NSF Gluten-Free certified; fermented ingredients absorb more readily; multiple functional blends (stress and energy support, cardio support, immune system support); several organic plant extracts
Price $21.69 for 30 servings ($0.72/serving)
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$45.99 for 60 servings ($0.77/serving)
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$55 for 96 servings ($0.57/serving)
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Best for: 40+ men looking for an all-in-one multivitamin that targets general well-being, prostate health, immunity, and much more.

Having personally met with Better Being (Solaray’s parent company) Chief Innovation and Science Officer Max Willis at Natural Products Expo East 2022, we understand what sets Solaray’s supplements apart. 

Solaray Men’s Golden Multivitamin is no exception, delivering 20+ letter vitamins and minerals alongside a Men’s Herbal Support Complex containing alfalfa herb, saw palmetto (great for prostate health), wild yam, and much more.

The biotin, zinc, selenium, and letter vitamins help to combat hair loss, and the smorgasbord of vitamins and minerals collectively supports immunity, cardiovascular health, hormonal stability, and many other benefits.

As for added ingredients, everything’s boilerplate as far as capsules are concerned: gelatin, soy, sucrose, cellulose, silica, and so forth.

Unless you’re really looking to lean into one benefit more than the other, Solaray Men’s Golden Multivitamin is our all-around top pick for men over 40. 

Best for: 40+ men as well as younger men looking for a long-term supplement to fill key nutritional gaps and prevent specific health issues.

While it’s not exclusively marketed to men over 40, Hi-Health Men’s Multi contains many of the same staple ingredients we find in 40+ men’s multivitamins: saw palmetto, nettle leaf extract, horsetail extract, betaine HCl, and many, many others.

Vitamin D, C, and other letter vitamins are covered, ranging in potency from 50% to 4167% daily value, as well as trace minerals like zinc, selenium, copper, manganese, and more.

The whole food blend uses extracts from garlic, broccoli, tomato, celery, parsley leaves, and more, and the energy support complex combines green tea, rosemary, and rutin, to name a few.

It will run you a bit more than the Solaray product listed above, but Hi-Health Men’s Multi fulfills a very similar role: a daily multivitamin that just about every man will benefit from.

Best for: Men who have had limited results with even high-quality multivitamins; men looking for a well-rounded multivitamin that absorbs easily.

It may not be the most alluring word on the more culinary side of nutrition, but fermented ingredients are a good thing in the multivitamin world.

To put it simply, fermented essential vitamins and minerals are partially pre-digested, meaning it takes less work for the body to break them down more completely, resulting in greater overall absorption.

New Chapter One Daily Every Man’s Multivitamin contains not just a couple, but 20 vitamins and minerals derived from ferment media, making it one of the best men’s multivitamins on the absorption front. 

In addition to the fermented letter vitamins, the three support blends (stress and energy, cardio, and immune) also provide wellness-affirming plant extracts, including the following:

  • Organic Maca root
  • Organic Schizandra berry
  • Organic Oregano leaf
  • Organic Eleuthero root
  • Organic European Elderberry extract

Especially if you’ve been underwhelmed by the effectiveness of men’s multivitamins in the past, we highly recommend New Chapter One Daily Every Man’s Multivitamin to achieve measurable results over time.

Best for: Men of a certain age looking to maintain or increase their performance in the gym, the workplace, and the bedroom as they get older.

Until now, we’ve knocked out three of our top multivitamins for men, but Mdrive Prime by DreamBrands is officially in “specialist” territory—that specialty being testosterone.

Using an extremely high-quality form of ashwagandha called KSM-66 ashwagandha, alongside tongkat ali extract, DHEA, black pepper fruit extract, chromium, and more, Mdrive Prime is intended to help your body naturally optimize its testosterone production.

Ashwagandha is so effective at supporting testosterone production, in fact, that one clinical trial (among many) reported a 14.7% increase in testosterone production in overweight male participants given the supplement. 

ashwagandha intake increases testosterone levels

Mdrive Prime also uses Chromax, a proprietary form of chromium, to enhance the testosterone’s effects on body fat reduction and lean muscle mass growth.

In other words, for guys in their 30s and beyond who aren’t quite feeling as vigorous as they used to, Mdrive Prime is an excellent option for safely and naturally restoring that testosterone level.

Best for: Ingredient quality purists who want the most natural multivitamin possible without sacrificing nutritional density.

Despite often being labeled in popular media as undiscerning, hot-wing-pounding gluttons (come on—they’re delicious), we men still care about organic ingredients. 

Answering this stifled call for ingredient integrity in the men’s multivitamin space with gusto is Garden of Life Vitamin Code for Men, which contains dozens of key micronutrients made from cultures of S. cerevisiae (brewer’s yeast). 

Deriving the vitamin C, vitamin D, iodine, selenium, chromium, and many other ingredients via fermentation helps with absorption, digestion, and more.

Speaking of digestion, Garden of Life Vitamin Code for Men also comes with a raw probiotic and enzyme blend, which features lipase, protease, lactase, and several other key enzymes and probiotics.

Most impressive, however, is the all-organic, whole-food-based fruit and vegetable blend, which includes a whopping 23 ingredients like apple, beet, green bell pepper, green onion, raspberry, and more.

Considering the standard vitamins and minerals and the organic blend, every common nutritional gap is addressed with Garden of Life Vitamin Code for Men

Best for: Men age 50 and up who want a potent, complete, and clean multivitamin they can take once a day and forget about.

As the most affordable option on our list of the best vitamins for men over 40, you’d think Nature’s Way Alive! would be a pared-down version of its costlier counterparts, but nay! (We’re bringing back “nay”).

In fact, there are more than 100 ingredients on the list, which fall into these categories:

  • Vitamins, minerals, and other micronutrients: Vitamins A-E and K, iodine, zinc, selenium, copper, chromium, and many others.
  • Prostate Blend: Saw palmetto, tomato extract (lycopene)
  • Orchard FruitsTM Blend: Pomegranate seed, acai extract, juice powders (cranberry, blackberry, cherry, and more)
  • Garden VeggiesTM Juice Powder Blend: Parsley, kale, spinach, wheat grass, brussels sprouts, cauliflower, and more
  • Mind and Body Energy Blend: Ginkgo biloba extract, Siberian eluthero, Rhodiola rosea, Korean ginseng, etc.
  • Cardiovascular Blend with Resveratrol: Hawthorn berry, Japanese knotweed.
  • Green Food/Spirulina Blend: Spirulina, alfalfa, dandelion, blessed thistle, chlorella, etc.
  • Organic Mushroom Defense Blend: Cordyceps, reishi, shiitake, chaga, mesima, etc.
  • Digestive Enzyme Blend: Protease (I and II), amylase, lactase, lipase, betaine HCl, etc.

This isn’t even the end of the blends and complexes, but we’re just going to stop here for brevity’s sake.

Suffice it to say, you get your money’s worth and then some with Nature’s Way Alive! Once Daily Men 50+, and without having to snarf down 3-4 tablets either.

FAQ About Vitamins for Men Over 40

Do men’s one-a-day vitamins work?

High-quality men’s vitamins such as those listed above, in conjunction with a healthy diet and exercise, may improve several aspects of overall health, including immunity, vision, heart health, and more. 

It’s important to note that the majority of men’s multivitamins are non-stimulating and non-psychoactive, meaning you are less likely to notice dramatic short-term effects with a product rather than gradual, long-term benefits.

Are men’s multivitamins worth it?

Whether or not any given multivitamin product is worth it for you can depend on subjective and/or situational factors, like your budget, your specific medical needs, and more. 

In general, men’s multivitamins cover such a broad range of key health needs that they’re often seen as worth it for people who don’t already follow extremely well-rounded diets. 

What vitamins should men not take?

Most vitamins, especially if they are already produced by the body and supplemented without harmful added ingredients, are safe to take if you adhere to dietary guidelines.

However, even healthy antioxidants like beta carotene can increase the risk of developing lung cancer when they are consumed in excess in supplement form, especially among smokers. 

Another category of risky supplements for men includes some erectile dysfunction (ED) supplements like yohimbe and goat weed, which have been associated with unhealthy spikes in blood pressure, nausea, allergic reactions, and more. 

This is not an exhaustive list, but determining exactly which vitamins are not appropriate for you depends on your medical situation, and may require a consultation with your doctor.

Should I take vitamins in the morning or at night?

While many daily vitamins for men don’t show a great discrepancy in their effectiveness associated with the time of day (or night) at which they’re taken, the body’s ability to absorb vitamins is generally better in the morning.

It’s helpful to take fat-soluble vitamins (A, D, E, and K) with a meal.

That said, neuroprotectants like vitamin E might best be taken at night.

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