The 7 Best Fish Oil Supplements for Healthy Hearts and Brains

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Dr. Jennifer Hughes, MD
Medical Reviewer

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As the evidence behind the heart-healthy, cognitive, and inflammation-fighting benefits of omega-3 fats is constantly growing, adding fish oil to your daily routine is a no-brainer—but choosing the right one is far less obvious. 

With different sources, varying doses of the primary omega-3 fats (EPA and DHA), and issues of purity and sustainability to think about, it is understandably difficult to pick a fish oil supplement—fortunately, we’ve got you covered.

In this article, check out our list of the seven best fish oil supplements, including our top pick, Nordic Naturals Ultimate Omega, and six others for every situation—whether you’re on a budget, hate taking pills, are dealing with joint pain, or trying to lower your cholesterol.

Best Overall: Nordic Naturals Ultimate Omega
  • Description

    Providing the purest and most ethical fish oil, Nordic Naturals takes our top spot with their Ultimate Omega capsules. Their “great lemon taste” more than adequately removes that classic fishy aftertaste and each capsule boasts an ideal amount of EPA and DHA.

Top 7 Best Fish Oil Supplements

Fish Oil SupplementKey PointsEPA/DHA DosageCost
Nordic Naturals Ultimate OmegaLemon flavor; 100% wild-caught sardines and anchovies; Focus on purity and freshness; High doses of EPA/DHA650mg EPA, 450mg DHA $49.95 for 60 servings ($0.83 per serving)
NOW Omega-3, Molecularly Distilled Molecular distillation removes impurities like heavy metals and PCBs; 3-month supply360mg EPA, 240mg DHA$19.99 for 100 servings ($0.20 per serving)
Nordic Naturals Omega-3 Liquid – LemonLemon flavor; High amounts of EPA/DHA; 100% wild-caught sardines and anchovies745mg EPA, 500mg DHA$25.95 for 48 servings ($0.54 per serving)
Wiley’s Finest Wild Alaskan Fish Oil Easy Swallow Minis55% smaller than most softgels without lowering EPA/DHA; From sustainable Alaskan fish 360mg EPA, 270mg DHA$44.99 for 90 servings ($0.50 per serving)
Nordic Naturals Ultimate Omega Gummy ChewsZero-sugar tropical fruit gummies; Third-party tested; Individually sealed for travel or on-the-go convenience600mg EPA, 450mg DHA$44.95 for 27 servings ($1.66 per serving)
Nordic Omega LDLContains red yeast rice for cholesterol and CoQ10 for heart health; Omega-3’s are from 100% wild sardines and anchovies585mg EPA, 405mg DHA$29.95 for 20 servings ($1.50 per serving)
Nordic Omega CurcuminContains curcumin and glutathione to fight inflammation and oxidative stress; Good for joint health 590mg EPA, 420mg DHA$49.95 for 30 servings ($1.67 per serving)

Best Overall: Nordic Naturals Ultimate Omega

Nordic Naturals Ultimate Omega
  • Pros
  • Lemon flavor
  • High-quality purity and freshness with COAs available on all products
  • High amounts of EPA and DHA per serving
  • Sustainably sourced fish
  • Cons
  • Leaning toward the more expensive side

Best for: Any adult looking for high-quality fish oil; general heart, inflammation, and mood support.

Our pick for best overall fish oil supplement is the Nordic Naturals Ultimate Omega

The Nordic Naturals Ultimate Omega is one of the highest-quality fish oils, containing a combined 1,100mg of EPA and DHA sourced from 100% wild-caught sardines and anchovies from Norway and the South Pacific, providing support to heart, brain, and joint health. 

With the lemon-flavored soft gels, you can avoid the unpleasant fishy aftertaste commonly found in other fish oil supplements.

According to Nordic Naturals, original research backs their fish oil’s ability to support healthy glucose levels, healthy lipid levels in professional athletes, bronchial health, and the body’s ability to respond to stress in a healthy way. 

Nordic Naturals also has a certificate of analysis (COA) available for all products, ensuring their fish oil’s purity and strength. 

Plus, Nordic Naturals’ fish oil products are Friend of the Sea Certified, which guarantees the fisheries maintain strict standards for fishing methods, by-catch reduction, and social accountability.

Best Budget Omega-3: NOW Omega-3

NOW Omega-3
  • Pros
  • Highly affordable
  • Molecular distillation removes impurities like heavy metals and PCBs
  • Bottle contains 3-month supply
  • Cons
  • Lower amounts of EPA and DHA per serving

Best for: People looking for an affordable fish oil supplement

The NOW Omega-3 supplement is a perfect choice for people on a budget who don’t want to compromise on quality. 

With a decades-long history of providing affordable supplements that have been tested for stability and purity, NOW is a great option for getting a moderate dose of fish oil. 

One of the ways that NOW ensures its fish oils’ purity is through molecular distillation, which removes impurities like heavy metals, PCBs, dioxins, saturated fats, and other undesirable compounds while leaving behind only the beneficial components of the fish oil. 

And at just $0.20 per serving—and a 3-month serving per bottle—you can’t beat the prices of NOW Omega-3.

Best Tasting Liquid Omega-3: Nordic Naturals Omega-3 Liquid

Nordic Naturals Omega-3 Liquid
  • Pros
  • Tasty lemon flavor with no fishy aftertaste
  • Higher doses of EPA and DHA
  • Affordable
  • Triglyceride molecular form may increase absorption
  • Cons
  • Difficult to travel with

Best for: People who prefer liquid over pills and want to avoid any semblance of fishy aftertaste (we don’t blame you).

With highly concentrated levels of EPA and DHA, the Nordic Naturals Omega-3 Liquid is ideal for people who have trouble taking pills. 

But don’t think that it will taste like the unpleasant cod liver oil that your great-grandmother tried to get you to take—this liquid omega-3 has a fresh lemon flavor with no fishy remnants. 

Even though it has high amounts of omega-3s—1560mg in total—this liquid supplement is still highly affordable, and the triglyceride molecular form of the fish oil may increase absorption to ensure you get the most bang for your buck. 

On the downside, this supplement would be tricky to travel with, making it best for at-home omega-3 dosing.

Easiest to Swallow Omega-3: Wiley’s Finest Wild Alaskan Fish Oil Easy Swallow Minis

Wiley's Finest Wild Alaskan Fish Oil Easy Swallow Minis
  • Pros
  • Easy to swallow soft gels
  • Affordable 3-month serving
  • From sustainable Alaskan fish
  • Cons
  • Lower EPA and DHA than others

Best for: Adults or teens who have trouble swallowing larger pills.

Wiley’s Finest Wild Alaskan Fish Oil Easy Swallow Minis are the best choice for people who want a pill form of omega-3s—but still don’t like taking them. 

With soft gels that are 55% smaller than competitors with the same amount of omega-3s, Wiley’s Finest has managed to concentrate the EPA and DHA into a tiny, easy-to-swallow package. 

As this supplement has lower amounts of EPA and DHA than several others on this list, Wiley’s Finest could be a great option for teens who have trouble swallowing pills. 

Plus, Wiley’s Finest is a family-owned company that creates their fish oil from sustainable Alaskan fish, and every batch is tested for harmful contaminants like mercury, PCBs, heavy metals, and radiation.

Best Omega-3 Gummy: Nordic Naturals Ultimate Omega Gummy Chews

Nordic Naturals Ultimate Omega Gummy Chews
  • Pros
  • Zero-sugar, tropical fruit flavor
  • High amounts of EPA and DHA
  • Individually sealed gummies are helpful for travel or on-the-go
  • Cons
  • Expensive
  • Only 27 servings per container

Best for: People who don’t like pills; people who want individually-sealed supplements for travel or on-the-go.

For people who like their supplements to taste like candy, Nordic Naturals Ultimate Omega Gummy Chews are the perfect option. 

Despite their tasty tropical fruit flavor, these gummies have zero sugar and are sweetened with stevia, xylitol, and erythritol. 
Although they are on the expensive side, the Nordic Naturals gummies pack a ton of EPA and DHA in each serving, totaling 1200mg of omega-3s to support heart, brain, and immune health.

Best Fish Oil for High Cholesterol: Nordic Omega LDL

Nordic Omega LDL
  • Pros
  • Contains red yeast rice and CoQ10 to support heart health
  • Provides antioxidant support
  • Moderately high amounts of concentrated fish oil
  • Cons
  • Expensive
  • Only 20 servings per container

Best for: People with high cholesterol or looking for extra cardiovascular support 

If you have high cholesterol or other heart health concerns, the Nordic Omega LDL may be the right pick for you. 

With 1152mg total omega-3s, 1200mg of red yeast rice powder, and 30mg of coenzyme Q10 (CoQ10), this supplement is loaded with ingredients that may reduce LDL (“bad”) cholesterol and improve heart health.

Red yeast rice has been found to support healthy cholesterol levels and cardiovascular and blood vessel function, while CoQ10 is an antioxidant that can protect cardiovascular cells from oxidative stress—the buildup of free radicals and reactive oxygen species that damage cells and DNA. 

However, this supplement is quite expensive and only carries 20 servings per container, which may not be a sustainable option for many people.

Best Joint Support Formula: Nordic Omega Curcumin

Nordic Omega Curcumin
  • Pros
  • Contains curcumin and glutathione to fight inflammation and oxidative stress
  • Moderately high amounts of EPA and DHA
  • Good for joint pain and cellular health
  • Cons
  • Most expensive on this list

Best for: People with joint pain or other inflammation-related conditions.

Lastly, the Nordic Omega Curcumin combines fish oil, curcumin, and the antioxidant glutathione to provide potent anti-inflammatory and antioxidant activity. 

Curcumin is the primary bioactive compound found in turmeric and has been well-studied for its role in fighting inflammation and reducing cellular damage—which can help with joint pain and disorders

Plus, the addition of glutathione further supports cellular health, as this compound is our body’s most abundant antioxidant. 

According to Nordic Naturals, the Omega Curcumin supplement “provides a foundation for cellular health and recovery.” 

While this is the most expensive omega-3 supplement on our list, the addition of curcumin and glutathione—which are not inexpensive supplements—may make it worthwhile for people dealing with inflammatory conditions to get a 3-in-1 combination supplement.

Fish Oil Supplements Buyers Guide

Not all fish oil supplements are created equal.

Many on the market are made with oxidized or rancid fish oil or have poor quality ingredients added, which can have a detrimental effect on your health.

Fish oil is one of the most important supplements to do your homework with—consider these factors when purchasing: 

  • Purity: The fish oil supplement should show third-party testing for contaminants like heavy metals (like mercury), dioxins, PCBs, and other organic industrial products. Brands (like Nordic Naturals and Wiley’s Finest) show COAs for products; others use molecular distillation to remove contaminants. 
  • Potency of dosage: If your fish oil does not contain adequate amounts of EPA and DHA, it likely won’t provide you with significant benefits. If a fish oil supplement simply states “total fish oils” but doesn’t specify how much EPA and DHA—it likely doesn’t have many. While there is no official recommended daily allowance for EPA and DHA, your fish oil should contain, at a minimum, 250mg of DHA and 250mg of EPA in healthy people. People with heart disease may benefit from doses up to 1,000mg of combined DHA and EPA.
  • Sustainability: Overfishing is a serious problem in our oceans. Nordic Naturals and Wiley’s Finest are two fish oil brands that focus on sustainability, which is verified, respectively, by their Friend of the Sea and Marine Stewardship Council (MSC) certifications. 
  • Freshness: Omega-3 fats are susceptible to oxidation and rancidity from light, oxygen, and heat, negating the nutritional benefits due to the production of pro-inflammatory compounds. Oxidized fish oil will have a notably pungent smell and “off” flavor. To preserve freshness, brands can use nitrogen instead of oxygen during the molecular distillation process, use airtight oxygen barrier containers when shipping products, add vitamin E (an antioxidant) to prevent oxidation, or show total oxidation levels in their third-party testing. 
  • Bioavailability: Lastly, the molecular shape of the fish oil may impact how well your body absorbs it. It’s suggested that the fish oils with the highest bioavailability are in the triglyceride form, which is how the oil is naturally found in the fish. The majority of fish oil supplements on the market—and the majority that are used in clinical research—are in the ethyl ester (“EE”) form, which is a semi-natural form made of concentrated natural triglyceride oil. Some research has found triglycerides to be better absorbed, but the data is not conclusive overall. However, one form to avoid is “synthetic triglyceride oil,” which is entirely man-made.

FAQs About Fish Oil Supplements

Are Fish Oil Supplements Good For You?

Yes, high-quality fish oil supplements with adequate doses of EPA and DHA are thought to be good for your health. 

Specifically, omega-3 fats are thought to be beneficial for cardiovascular, metabolic, and immune health, and possibly cognitive function and mood.

Research hasn’t consistently shown that fish oil supplements reduce the risk of heart disease. 

However, fish oil or omega-3s have shown promise for reducing risk factors of cardiovascular disease, including high blood pressure, arrhythmias, high cholesterol, and atherosclerosis—the buildup of plaque in arteries that causes arterial thickening or hardening.

What Is The Best Fish Supplement To Take?

The best fish oil supplements to take are those emphasizing purity, EPA and DHA potency, sustainability, freshness, and bioavailability. 

Our favorite fish oil brand is Nordic Naturals

Is It Good To Take Fish Oil Everyday?

Fish oil is most likely safe for most people to take every day. 

However, people with severe seafood allergies may want to get their omega-3s from a plant-based source, like algae. 

Also, as fish oil has a blood-thinning effect—which is why it’s helpful for cardiovascular health—people with bleeding disorders or liver disease can have an increased risk of bleeding from fish oil. 

Can You Take Too Much Fish Oil?

Yes, you can take too much fish oil. 

The FDA recommends not exceeding exceed 3g per day of EPA and DHA combined from all sources, with no more than 2g per day deriving from fish oil or omega-3 supplements.

How Can You Tell If Fish Oil Is High Quality?

A fish oil supplement is high-quality if:

● It shows evidence of third-party testing for heavy metals and contaminants
● Has more than 250mg each of EPA and DHA (ideally 1,000mg combined)
● Uses sustainably sourced fish
● Has measures in place to ensure freshness and prevention of oxidation. 

Who Shouldn’t Take Fish Oil?

People with severe seafood allergies may want to avoid fish oil. 

Also, people with bleeding disorders or liver disease can have an increased risk of bleeding from fish oil. 

Lastly, people on anticoagulant medications (blood thinners) should discuss the use of omega-3 or fish oil supplements with their healthcare provider.

Key Takeaways

  • Fish oil supplements are rich in the omega-3 fatty acids EPA and DHA, which have shown promise for supporting cardiovascular, metabolic, immune, and cognitive health. 
  • However, many fish oil supplements utilize low-quality oils that are rancid, oxidized, or in low doses. 
  • Look for fish oil brands that utilize third-party testing for heavy metals and contaminants, contain more than 250mg each of EPA and DHA (ideally 1,000mg combined), use sustainably sourced fish, and have measures in place to ensure freshness and prevention of oxidation. 

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